Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorene SCHEMBL27662337 | 0.85 | HTR2B (0.56) | HTR2BHTR2CMAOACYP1A2ADRA2A | |
| Fluorene SCHEMBL28112745 | 0.85 | MAOA (0.58) | HTR2BHTR2CMAOACYP1A2ADRA2A | |
| Fluorene SCHEMBL23421425 | 0.84 | CYP1A2 (0.51) | HTR2BHTR2CMAOACYP1A2ADRA2A | |
| Fluorene SCHEMBL6872049 | 0.83 | SRD5A2 (0.60) | HTR2BHTR2CMAOACYP1A2ADRA2A | |
| Fluorene SCHEMBL2673075 | 0.82 | GABRP (0.56) | HTR2BHTR2CMAOACYP1A2ADRA2A | |
| Fluorene SCHEMBL27664493 | 0.81 | MAOA (0.54) | HTR2BHTR2CMAOACYP1A2ADRA2A | |
| Methyl Carbamate SCHEMBL9587539 | 0.81 | HSD17B3 (0.44) | RAB9AKDM4EALDH1A1MAPTHPGD | |
| Fluorene SCHEMBL28255479 | 0.80 | MAOA (0.56) | HTR2BHTR2CMAOACYP1A2ADRA2A | |
| Fluorene SCHEMBL2708609 | 0.79 | TSHR (0.68) | HTR2BHTR2CMAOACYP1A2ADRA2A | |
| Fluorene SCHEMBL27744834 | 0.79 | CYP1A2 (0.51) | HTR2BHTR2CMAOACYP1A2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721630-A | A kind of synthetic method of Ugi ' s amine and its derivative | 上海茂晟康慧科技有限公司 | 2019-05-07 | — | — | CN | claimed |
| CN-116947919-A | Fmoc-benzhydrylamine derivatives for synthesis of carbon-terminal amidated polypeptides and method for preparing same | 山西医科大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-114751920-A | Antitumor compounds | 法马马有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-110183461-A | Cortex chalone analog and its synthesis and purposes | 哈佛学院院长等 | 2019-08-30 | — | — | CN | disclosed |
| CN-106103452-B | Cortictatin analogs, their synthesis and use | 哈佛学院院长等 | 2019-05-21 | — | — | CN | disclosed |
| CN-109721630-A | A kind of synthetic method of Ugi ' s amine and its derivative | 上海茂晟康慧科技有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-109562122-A | Oligonucleotides, composition and its method | 波涛生命科学有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-109462995-A | The method and composition of bioactivator | 波涛生命科学有限公司 | 2019-03-12 | — | — | CN | disclosed |
| CN-109219436-A | modified wound dressing | 康沃特克科技公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-109136974-A | One kind (sp containing C2)-N key compound preparation method | 中国科学院上海有机化学研究所 | 2019-01-04 | — | — | CN | disclosed |
| CN-104292394-B | Preparation method of Rink amide resin | 深圳微球科技有限公司 | 2017-02-08 | — | — | CN | disclosed |
| CN-106103452-A | Cortictatin analogs, their synthesis and use | 哈佛学院院长等 | 2016-11-09 | — | — | CN | disclosed |
| CN-105849099-A | Polycyclic inhibitors of cyclin-dependent kinase 7 (CDK7) | 达纳-法伯癌症研究所股份有限公司 | 2016-08-10 | — | — | CN | disclosed |
| CN-105792852-A | Glucose-responsive insulin conjugates | 默沙东公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-105705143-A | Nucleic acid nanostructures for in vivo agent delivery | 达娜-法勃肿瘤研究所公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-101346468-B | amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-03-30 | — | — | CN | disclosed |
| CN-104487485-A | Polycarbonate polyol compositions and methods | NOVOMER INC | 2015-04-01 | — | — | CN | disclosed |
| US-8895231-B2 | Patterning process and resist composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-11-25 | — | — | US | disclosed |
| US-20120058428-A1 | PATTERNING PROCESS AND RESIST COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-03-08 | — | — | US | disclosed |
| CN-101346468-A | Amine-containing lipids and uses thereof | MASSACHUSETTS INST TECHNOLOGY (US) | 2009-01-14 | — | — | CN | disclosed |