Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.66 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445705 | 1.00 | MAOB (0.66) | MAOBMAOALMNAGAACYP3A4 | |
| SCHEMBL148925 | 0.93 | MAOB (0.68) | MAOBMAOALMNAGAACYP3A4 | |
| Sulfuric Acid SCHEMBL141163 | 0.86 | MAOB (0.77) | MAOBMAOALMNACYP2D6BCHE | |
| Sulfuric Acid SCHEMBL141164 | 0.85 | MAOB (0.74) | MAOBMAOALMNACYP2D6BCHE | |
| SCHEMBL9011427 | 0.83 | MAOB (0.62) | MAOBMAOALMNACYP2D6HTT | |
| SCHEMBL8008700 | 0.82 | MAOB (0.70) | MAOBMAOALMNAGAACYP2D6 | |
| SCHEMBL31231150 | 0.81 | MAOB (1.00) | MAOBMAOALMNACYP2D6HTT | |
| SCHEMBL30311 | 0.81 | MAOB (1.00) | MAOBMAOALMNACYP2D6HTT | |
| Bromide SCHEMBL1821620 | 0.79 | MAOB (0.96) | MAOBMAOALMNACYP2D6HTT | |
| SCHEMBL8530667 | 0.79 | MAOB (0.96) | MAOBMAOALMNACYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274056-B1 | BLEACHING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOCHINOLINIUM DERIVATIVES, SPECIFIC ALKANOLAMINES AND HYDROGEN PEROXYDE | HENKEL AG & CO KGAA (DE) | 2012-10-03 | — | — | EP | claimed |
| US-20110146005-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | GROSS WIBKE | 2011-06-23 | — | — | US | claimed |
| EP-2315614-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | Henkel AG & Co. KGaA (DE) | 2011-05-04 | — | — | EP | claimed |
| EP-2274056-A1 | BLEACHING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOQUINOLINE DERIVATES, SPECIAL ALKANOL AMINES AND HYDROGEN PEROXIDE | Henkel AG & Co. KGaA (DE) | 2011-01-19 | — | — | EP | claimed |
| EP-2192957-A1 | BRIGHTENING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOQUINOLINE DERIVATIVES AND HYDROGEN PEROXIDE | Henkel AG & Co. KGaA (DE) | 2010-06-09 | — | — | EP | claimed |
| WO-2010022995-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | HENKEL AG & CO. KGAA (DE) | 2010-03-04 | — | — | WO | claimed |
| WO-2009138259-A1 | BLEACHING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOQUINOLINE DERIVATES, SPECIAL ALKANOL AMINES AND HYDROGEN PEROXIDE | HENKEL AG & CO. KGAA (DE) | 2009-11-19 | — | — | WO | claimed |
| WO-2009043613-A1 | BRIGHTENING AGENT COMPRISING CATIONIC 3,4-DIHYDROISOQUINOLINE DERIVATIVES AND HYDROGEN PEROXIDE | HENKEL AG & CO. KGAA (DE) | 2009-04-09 | — | — | WO | claimed |
| EP-1280881-B1 | MACHINE DISHWASHING COMPOSITIONS CONTAINING BLEACHING AGENTS AND POLYMERS | UNILEVER PLC (GB) | 2006-09-13 | — | — | EP | claimed |
| US-6602836-B2 | Machine dishwashing compositions containing cationic bleaching agents and water-soluble polymers incorporating cationic groups | UNILEVER HOME & PERSONAL CARE USA, A DIVISION OF CONOPCO, INC. | 2003-08-05 | — | — | US | claimed |
| US-20030073596-A1 | Machine dishwashing compositions containing cationic bleaching agents and water-soluble polymers incorporating cationic groups | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-04-17 | — | — | US | claimed |
| US-20250250514-A1 | COMPOSITION | KAO CORPORATION (JP) | 2025-08-07 | — | — | US | disclosed |
| EP-4509486-A1 | COMPOSITION | Kao Corporation (JP) | 2025-02-19 | — | — | EP | disclosed |
| CN-117448299-A | Lipase variants and microcapsule compositions comprising such lipase variants | 诺维信公司 | 2024-01-26 | — | — | CN | disclosed |
| WO-2023199939-A1 | COMPOSITION | 花王株式会社 | 2023-10-19 | — | — | WO | disclosed |
| EP-0728182-B1 | IMINE SALTS AS BLEACH CATALYSTS | UNILEVER NV (NL) | 1997-09-03 | — | — | EP | disclosed |
| US-5550256-A | OXYGEN TRANSFER AGENT | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1996-08-27 | — | — | US | disclosed |
| US-5478357-A | Using an oxygen transfer agent | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1995-12-26 | — | — | US | disclosed |
| US-5360569-A | Peroxygen bleaches with oxygen transfer agent of isoquinolium compound and forming percarboxylic, percarbonic acid or perimidic acid | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1994-11-01 | — | — | US | disclosed |
| US-5360568-A | 3,4-dihydroisoquinolinium salt and peroxygen compound mixture; low temperature | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1994-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110146005-A1 | CATIONIC DIHYDROISOQUINOLINIUM DERIVATIVES FOR USE AS BLEACH ACTIVATORS | KRT18, QDPR, DSG1 | MAOB 874/4885MAOA 534/4885LMNA 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.