Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.66 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147387 | 1.00 | MAOB (0.66) | MAOBMAOALMNAGAACYP3A4 | |
| SCHEMBL148925 | 0.93 | MAOB (0.68) | MAOBMAOALMNAGAACYP3A4 | |
| Sulfuric Acid SCHEMBL141163 | 0.86 | MAOB (0.77) | MAOBMAOALMNACYP2D6BCHE | |
| Sulfuric Acid SCHEMBL141164 | 0.85 | MAOB (0.74) | MAOBMAOALMNACYP2D6BCHE | |
| SCHEMBL9011427 | 0.83 | MAOB (0.62) | MAOBMAOALMNACYP2D6HTT | |
| SCHEMBL8008700 | 0.82 | MAOB (0.70) | MAOBMAOALMNAGAACYP2D6 | |
| SCHEMBL31231150 | 0.81 | MAOB (1.00) | MAOBMAOALMNACYP2D6HTT | |
| SCHEMBL30311 | 0.81 | MAOB (1.00) | MAOBMAOALMNACYP2D6HTT | |
| Bromide SCHEMBL1821620 | 0.79 | MAOB (0.96) | MAOBMAOALMNACYP2D6HTT | |
| SCHEMBL8530667 | 0.79 | MAOB (0.96) | MAOBMAOALMNACYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459939-B | Lipase variants and polynucleotides encoding same | 诺维信公司 | 2026-05-22 | — | — | CN | disclosed |
| US-20260132388-A1 | LIPASE VARIANTS AND MICROCAPSULE COMPOSITIONS COMPRISING SUCH LIPASE VARIANTS | NOVOZYMES A/S (DK) | 2026-05-14 | — | — | US | disclosed |
| EP-4717756-A2 | LIPASE VARIANTS AND DETERGENT COMPOSITIONS | Novozymes A/S (DK) | 2026-04-01 | — | — | EP | disclosed |
| US-12559736-B2 | Lipase variants and polynucleotides encoding same | NOVOZYMES A/S (DK) | 2026-02-24 | — | — | US | disclosed |
| US-12529017-B2 | Detergent composition comprising a lipase | NOVOZYMES A/S (DK) | 2026-01-20 | — | — | US | disclosed |
| US-20250382594-A1 | METHODS OF REDUCING ODOR | NOVOZYMES A/S (DK) | 2025-12-18 | — | — | US | disclosed |
| US-12492387-B2 | Lipase variants and microcapsule compositions comprising such lipase variants | NOVOZYMES A/S (DK) | 2025-12-09 | — | — | US | disclosed |
| US-20250368924-A1 | LIPASE VARIANTS AND COMPOSITIONS COMPRISING SUCH LIPASE VARIANTS | NOVOZYMES A/S (DK) | 2025-12-04 | — | — | US | disclosed |
| US-12480107-B2 | Lipase variants and the use thereof | NOVOZYMES A/S (DK) | 2025-11-25 | — | — | US | disclosed |
| US-12480108-B2 | Methods of reducing odor | Novozyms A/S (DK) | 2025-11-25 | — | — | US | disclosed |
| US-11332725-B2 | Lipase variants and microcapsule compositions comprising such lipase variants | NOVOZYMES A/S (DK) | 2022-05-17 | — | — | US | disclosed |
| US-20220145273-A1 | LIPASE VARIANTS AND POLYNUCLEOTIDES ENCODING SAME | NOVOZYMES A/S (DK) | 2022-05-12 | — | — | US | disclosed |
| EP-3994255-A1 | LIPASE VARIANTS AND COMPOSITIONS THEREOF | Novozymes A/S (DK) | 2022-05-11 | — | — | EP | disclosed |
| US-11326152-B2 | Lipase variants, polynucleotides encoding same and the use thereof | NOVOZYMES A/S (DK) | 2022-05-10 | — | — | US | disclosed |
| US-11326153-B2 | Alpha-amylase variants and polynucleotides encoding same | NOVOZYMES A/S (DK) | 2022-05-10 | — | — | US | disclosed |
| WO-2022090361-A2 | LIPASE VARIANTS AND COMPOSITIONS COMPRISING SUCH LIPASE VARIANTS | NOVOZYMES A/S (DK) | 2022-05-05 | — | — | WO | disclosed |
| US-11312946-B2 | Detergent compositions | NOVOZYMES A/S (DK) | 2022-04-26 | — | — | US | disclosed |
| CN-114292829-A | Lipase variants and polynucleotides encoding same | 诺维信公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-114207123-A | Lipase variants and compositions thereof | 诺维信公司 | 2022-03-18 | — | — | CN | disclosed |
| US-11268076-B2 | Lipase variants and polynucleotides encoding same | NOVOZYMES A/S (DK) | 2022-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559736-B2 | Lipase variants and polynucleotides encoding same | LPL, PNLIP, LIPG | MAOB 1080/4885MAOA 1184/4885LMNA 512/4885 |
| US-11312946-B2 | Detergent compositions | DAGLB, ABHD16A, DAGLA | MAOB 3043/4885MAOA 3892/4885LMNA 521/4885 |
| US-20260132388-A1 | LIPASE VARIANTS AND MICROCAPSULE COMPOSITIONS COMPRISING SUCH LIPASE VARIANTS | LIPE, LPL, PNLIP | MAOB 1197/4885MAOA 1909/4885LMNA 977/4885 |
| US-12529017-B2 | Detergent composition comprising a lipase | MGLL, LPL, LIPC | MAOB 2721/4885MAOA 2245/4885LMNA 2201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.