Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | HTR1A | P08908 | 5/20 | 0.58 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | SOD1 | P00441 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670409 | 0.88 | DRD2 (0.68) | DRD2HSD17B10MEN1KMT2AHTR1A | |
| SCHEMBL5915124 | 0.86 | DRD2 (1.00) | DRD2HSD17B10MEN1KMT2AHTR1A | |
| SCHEMBL9559845 | 0.85 | DRD2 (0.73) | DRD2HSD17B10MEN1KMT2AHTR1A | |
| SCHEMBL19099996 | 0.85 | DRD2 (0.73) | DRD2HSD17B10MEN1KMT2AHTR1A | |
| SCHEMBL4251574 | 0.85 | HSD17B10 (0.82) | DRD2HSD17B10MEN1KMT2AHTR1A | |
| SCHEMBL2109825 | 0.85 | DRD2 (0.73) | DRD2HSD17B10MEN1KMT2AHTR1A | |
| Hydrochloric Acid SCHEMBL11218267 | 0.85 | DRD2 (0.97) | DRD2HSD17B10MEN1KMT2AHTR1A | |
| SCHEMBL18937451 | 0.83 | DRD2 (0.82) | DRD2HSD17B10MEN1KMT2AHTR1A | |
| Hydrochloric Acid SCHEMBL11456534 | 0.83 | DRD2 (0.71) | DRD2HSD17B10MEN1KMT2AHTR1A | |
| Hydrochloric Acid SCHEMBL11447131 | 0.83 | DRD2 (0.71) | DRD2HSD17B10MEN1KMT2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9212143-B2 | Small molecule inhibitors of protein kinases | LEVOLTA PHARMACEUTICALS, INC. (US) | 2015-12-15 | — | — | US | disclosed |
| US-20130058980-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES | LEVOLTA PHARMACEUTICALS, INC. | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130058980-A1 | SMALL MOLECULE INHIBITORS OF PROTEIN KINASES | SYK, BTK, LCK | DRD2 4144/4885HSD17B10 4430/4885MEN1 2031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.