Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.56 |
| ▸ | HTR3B | O95264 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.56 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.56 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | IGF1R | P08069 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14739618 | 0.88 | DRD2 (0.76) | DRD2HSD17B10KMT2AMEN1HTR3E | |
| SCHEMBL29656856 | 0.84 | HTR3E (0.73) | DRD2HSD17B10KMT2AMEN1HTR3E | |
| SCHEMBL28599511 | 0.84 | HTR3E (0.73) | DRD2HSD17B10KMT2AMEN1HTR3E | |
| SCHEMBL8353109 | 0.84 | DRD2 (0.75) | DRD2HSD17B10KMT2AMEN1HTR3E | |
| SCHEMBL9668818 | 0.83 | MAPT (0.53) | DRD2HSD17B10KMT2AMEN1ALDH1A1 | |
| SCHEMBL23572815 | 0.82 | DRD2 (0.48) | DRD2HSD17B10KMT2AMEN1SIGMAR1 | |
| SCHEMBL21361433 | 0.82 | DRD2 (0.68) | DRD2HSD17B10KMT2AMEN1HTR3E | |
| SCHEMBL12789832 | 0.82 | DRD2 (0.68) | DRD2HSD17B10KMT2AMEN1HTR3E | |
| SCHEMBL9449554 | 0.81 | KCNH2 (0.70) | DRD2KMT2AMEN1ADRB1ALDH1A1 | |
| SCHEMBL5915124 | 0.81 | DRD2 (1.00) | DRD2HSD17B10KMT2AMEN1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254322-B1 | BENZIMIDAZOLE DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-09-23 | — | — | EP | claimed |
| US-4886803-A | CARDIOTONIC AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-12-12 | — | — | US | claimed |
| EP-0254322-A1 | Benzimidazole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-01-27 | — | — | EP | claimed |
| EP-0254322-B1 | BENZIMIDAZOLE DERIVATIVES | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1992-09-23 | — | — | EP | disclosed |
| US-4886803-A | CARDIOTONIC AGENTS | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1989-12-12 | — | — | US | disclosed |
| EP-0254322-A1 | Benzimidazole derivatives | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1988-01-27 | — | — | EP | disclosed |
| EP-0186977-A2 | Renin-inhibitory dipeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1986-07-09 | — | — | EP | disclosed |
| US-4199519-A | TREATMENT OF PEPTIC ULCERS | SANKYO COMPANY LIMITED (JP) | 1980-04-22 | — | — | US | disclosed |
| US-4151357-A | FOR PEPTIC ULCERS | SANKYO COMPANY LIMITED (JP) | 1979-04-24 | — | — | US | disclosed |