Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5192732 | 0.91 | KMT2A (0.58) | GLAKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9693024 | 0.83 | LTA4H (0.46) | GLAKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL445495 | 0.81 | CTNNB1 (0.44) | GLAKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL240664 | 0.80 | NQO2 (0.57) | GLAKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL1441005 | 0.79 | CTNNB1 (0.43) | GLAKMT2AALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL15271481 | 0.79 | NQO2 (0.56) | GLAKMT2AALDH1A1KDM4EHPGD | |
| Hydrochloric Acid SCHEMBL32690198 | 0.77 | NQO2 (0.54) | GLAKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL441860 | 0.77 | KCNA3 (0.58) | GLAKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL29860318 | 0.77 | KCNA3 (0.58) | GLAKMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL222907 | 0.76 | ALDH1A1 (0.50) | GLAKMT2AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961801-B | A kind of synthesis and application of antibacterial polypeptide conjugate and its dimer with Mutiple Targets | 兰州大学 | 2018-01-19 | — | — | CN | disclosed |
| US-9090640-B2 | Targeted delivery and prodrug designs for platinum-acridine anti-cancer compounds and methods thereof | WAKE FOREST UNIVERSITY | 2015-07-28 | — | — | US | disclosed |
| US-20140193334-A1 | Targeted Delivery and Prodrug Designs for Platinum-Acridine Anti-Cancer Compounds and Methods Thereof | WAKE FOREST UNIVERSITY | 2014-07-10 | — | — | US | disclosed |
| WO-2013033430-A1 | TARGETED DELIVERY AND PRODRUG DESIGNS FOR PLATINUM-ACRIDINE ANTI-CANCER COMPOUNDS AND METHODS THEREOF | WAKE FOREST SCHOOL OF MEDICINE (US) | 2013-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140193334-A1 | Targeted Delivery and Prodrug Designs for Platinum-Acridine Anti-Cancer Compounds and Methods Thereof | ERBB3, EGFR, ESR1 | GLA 4641/4885KMT2A 4389/4885ALDH1A1 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.