Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7769205 | 0.98 | ALDH1A1 (0.49) | ALDH1A1GAAKMT2AGLAHPGD | |
| SCHEMBL5192732 | 0.80 | KMT2A (0.58) | ALDH1A1GAAKMT2AGLAHPGD | |
| SCHEMBL8740692 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KMT2AGLAHPGDRAB9A | |
| SCHEMBL3482649 | 0.79 | ALDH1A1 (0.43) | ALDH1A1GAAKMT2AGLAHPGD | |
| SCHEMBL214710 | 0.79 | ALDH1A1 (0.42) | ALDH1A1GAAKMT2AGLAHPGD | |
| SCHEMBL240664 | 0.77 | NQO2 (0.57) | ALDH1A1GAAKMT2AGLAHPGD | |
| SCHEMBL28934937 | 0.77 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2AGLAHPGD | |
| SCHEMBL28934949 | 0.77 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2AGLAHPGD | |
| SCHEMBL28934913 | 0.77 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2AGLAHPGD | |
| SCHEMBL28934953 | 0.77 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2AGLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190175566-A1 | ANTI-TUMOR COCKTAIL COMPRISING AN ANTI-TUMOR AGENT SELECTIVE FOR TUMOR ACIDITY, AN ANTIOXIDANT, AND A P-GLYCOPROTEIN INHIBITOR | ARION TECNOLOGIA BRASIL - GESTÃO DE ATIVOS S/A (BR) | 2019-06-13 | — | — | US | claimed |
| EP-1301485-B1 | NOVEL HETEROARYL DERIVATIVES AND THE USE THEREOF AS PHARMACEUTICALS | ZENTARIS GMBH (DE) | 2007-06-27 | — | — | EP | claimed |
| US-20050009809-A1 | Aryl- and heteroaryl-substituted piperazinylcarbonyl acridines and their homologs, e.g., (1,3-dihydroxyacridin-9-yl)-[4-(6-methyl pyridin-2-yl )piperazin-1-yl]methanone,are suitable for treating benign and malignant tumors | ZENTARIS GMBH (DE) | 2005-01-13 | — | — | US | claimed |
| US-6706722-B2 | IN PARTICULAR FOR TREATING TUMORS. | ZENTARIS AG (DE) | 2004-03-16 | — | — | US | claimed |
| US-20020132821-A1 | Novel heteroaryl derivatives and their use as medicaments | ZENTARIS GMBH (DE) | 2002-09-19 | — | — | US | claimed |
| EP-0725651-B1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1999-08-11 | — | — | EP | claimed |
| US-5830867-A | Hemoregulatory peptides for stimulating the myelopoietic system | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-03 | — | — | US | claimed |
| US-5652219-A | Hemoregulatory peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-29 | — | — | US | claimed |
| EP-0701446-A4 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1997-04-23 | — | — | EP | claimed |
| EP-0621788-A4 | HEMOREGULATORY PEPTIDES. | SMITHKLINE BEECHAM CORP (US) | 1997-03-05 | — | — | EP | claimed |
| EP-0725651-A4 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORP (US) | 1997-03-05 | — | — | EP | claimed |
| EP-0725651-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-14 | — | — | EP | claimed |
| EP-0701446-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1996-03-20 | — | — | EP | claimed |
| WO-1995011693-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-05-04 | — | — | WO | claimed |
| WO-1994027627-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-12-08 | — | — | WO | claimed |
| WO-1994028420-A1 | METHOD OF DETECTION OF BACTERIA | RHONE POULENC DIAGNOSTICS LTD (GB) | 1994-12-08 | — | — | WO | claimed |
| EP-0621788-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-11-02 | — | — | EP | claimed |
| WO-1993013789-A1 | HEMOREGULATORY PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-07-22 | — | — | WO | claimed |
| WO-2025070135-A1 | HEXAVALENT-CHROMIUM-REDUCING PHOTOCATALYST COMPOSITION AND METHOD FOR REDUCING HEXAVALENT CHROMIUM | ユシロ化学工業株式会社 | 2025-04-03 | — | — | WO | disclosed |
| US-4451474-A | T-Butyl-phenoxy-alkylene esters of benzoic and nicotinic acids, compositions containing same and their antihistaminic method of use | Berger, Frank M. (US) | 1984-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050009809-A1 | Aryl- and heteroaryl-substituted piperazinylcarbonyl acridines and their homologs, e.g., (1,3-dihydroxyacridin-9-yl)-[4-(6-methyl pyridin-2-yl )piperazin-1-yl]methanone,are suitable for treating benign and malignant tumors | PKD1, MDH2, MSH2 | ALDH1A1 23/4885GAA 3585/4885KMT2A 1945/4885 |
| US-20190175566-A1 | ANTI-TUMOR COCKTAIL COMPRISING AN ANTI-TUMOR AGENT SELECTIVE FOR TUMOR ACIDITY, AN ANTIOXIDANT, AND A P-GLYCOPROTEIN INHIBITOR | ABCG2, SDHA, ABCB1 | ALDH1A1 444/4885GAA 51/4885KMT2A 3489/4885 |
| US-20020132821-A1 | Novel heteroaryl derivatives and their use as medicaments | ABCB1, ABCB11, FANCD2 | ALDH1A1 173/4885GAA 483/4885KMT2A 3990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.