Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | NQO1 | P15559 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | NT5E | P21589 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.38 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.38 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CASP6 | P55212 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6818347 | 0.88 | AURKA (0.50) | AURKAAURKBNQO1ALDH1A1HSD17B10 | |
| SCHEMBL3260824 | 0.87 | AURKA (0.49) | AURKAAURKBNQO1ALDH1A1HSD17B10 | |
| SCHEMBL461765 | 0.86 | TNNI3 (0.42) | AURKAAURKBALDH1A1HSD17B10NT5E | |
| SCHEMBL21113847 | 0.86 | TNNI3 (0.42) | AURKAAURKBNQO1ALDH1A1HSD17B10 | |
| SCHEMBL461763 | 0.86 | TNNI3 (0.42) | AURKAAURKBNQO1ALDH1A1HSD17B10 | |
| SCHEMBL31229289 | 0.86 | AURKA (0.46) | AURKAAURKBNQO1ALDH1A1HSD17B10 | |
| SCHEMBL29384070 | 0.86 | AURKA (0.46) | AURKAAURKBNQO1ALDH1A1HSD17B10 | |
| SCHEMBL338441 | 0.86 | AURKA (0.46) | AURKAAURKBNQO1ALDH1A1HSD17B10 | |
| SCHEMBL572527 | 0.85 | AURKA (0.50) | AURKAAURKBNQO1ALDH1A1HSD17B10 | |
| SCHEMBL29393812 | 0.85 | AURKA (0.50) | AURKAAURKBNQO1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180074015-A1 | Fluorescent pI Markers for Isoelectric Focusing Separations and Fluorescent Labeling | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2018-03-15 | — | — | US | disclosed |
| US-9689841-B2 | Fluorescent pI markers for isoelectric focusing separations and fluorescent labeling | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2017-06-27 | — | — | US | disclosed |
| US-20140377875-A1 | FLUORESCENT PI MARKERS FOR ISOELECTRIC FOCUSING SEPARATIONS AND FLUORESCENT LABELING | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2014-12-25 | — | — | US | disclosed |
| WO-2013033046-A2 | FLUORESCENT PL MARKERS FOR ISOELECTRIC FOCUSING SEPARATIONS AND FLUORESCENT LABELING | VIGH GYULA (US) | 2013-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180074015-A1 | Fluorescent pI Markers for Isoelectric Focusing Separations and Fluorescent Labeling | PDAP1, PAIP1, IK | AURKA 1604/4885AURKB 1759/4885NQO1 4585/4885 |
| US-20140377875-A1 | FLUORESCENT PI MARKERS FOR ISOELECTRIC FOCUSING SEPARATIONS AND FLUORESCENT LABELING | PLG, PDAP1, PITPNB | AURKA 1350/4885AURKB 1629/4885NQO1 4634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.