Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22372188 | 0.91 | PHLPP2 (0.45) | GAAALDH1A1MAPK1HSD17B10MAPT | |
| SCHEMBL3008544 | 0.83 | LMNA (0.54) | ALDH1A1TSHRL3MBTL1MAPK1HSD17B10 | |
| SCHEMBL3004724 | 0.82 | LMNA (0.49) | ALDH1A1TSHRL3MBTL1MAPK1HSD17B10 | |
| SCHEMBL3010778 | 0.81 | LMNA (0.50) | ALDH1A1TSHRMAPK1HSD17B10MAPT | |
| SCHEMBL13092513 | 0.81 | LMNA (0.50) | ALDH1A1TSHRMAPK1HSD17B10MAPT | |
| SCHEMBL2995184 | 0.81 | LMNA (0.50) | ALDH1A1TSHRMAPK1HSD17B10MAPT | |
| SCHEMBL3006729 | 0.81 | LMNA (0.50) | ALDH1A1TSHRMAPK1HSD17B10MAPT | |
| SCHEMBL28575733 | 0.80 | LMNA (0.37) | ALDH1A1TSHRL3MBTL1MAPTLMNA | |
| SCHEMBL25475161 | 0.80 | FNTA (0.33) | ALDH1A1MAPTLMNASMN1; SMN2APP | |
| SCHEMBL3015836 | 0.80 | ALDH1A1 (0.44) | ALDH1A1TSHRHSD17B10MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033046-A2 | FLUORESCENT PL MARKERS FOR ISOELECTRIC FOCUSING SEPARATIONS AND FLUORESCENT LABELING | VIGH GYULA (US) | 2013-03-07 | — | — | WO | disclosed |