Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3008544 | 0.84 | LMNA (0.54) | LMNATSHRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL3004724 | 0.83 | LMNA (0.49) | LMNATSHRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL3006729 | 0.81 | LMNA (0.50) | LMNATSHRKDM4EALDH1A1CYP3A4 | |
| SCHEMBL2995184 | 0.81 | LMNA (0.50) | LMNATSHRKDM4EALDH1A1CYP3A4 | |
| SCHEMBL3010778 | 0.81 | LMNA (0.50) | LMNATSHRKDM4EALDH1A1CYP3A4 | |
| SCHEMBL13092513 | 0.81 | LMNA (0.50) | LMNATSHRKDM4EALDH1A1CYP3A4 | |
| SCHEMBL14742161 | 0.80 | GAA (0.51) | LMNAAPPTSHRKDM4EALDH1A1 | |
| SCHEMBL25475161 | 0.80 | FNTA (0.33) | LMNAAPPALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3015836 | 0.80 | ALDH1A1 (0.44) | LMNATSHRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL9212743 | 0.80 | LMNA (0.33) | LMNAAPPALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109336944-B | Tripterine imidazole derivative and preparation method and application thereof | 中国药科大学 | 2021-04-27 | — | — | CN | disclosed |