Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.70 |
| ▸ | KDR | P35968 | 3/20 | 0.70 |
| ▸ | RET | P07949 | 1/20 | 0.70 |
| ▸ | KIT | P10721 | 1/20 | 0.70 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.70 |
| ▸ | FLT3 | P36888 | 1/20 | 0.70 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.53 |
| ▸ | TEK | Q02763 | 1/20 | 0.53 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.53 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 2/20 | 0.46 |
| ▸ | MST1R | Q04912 | 1/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14742573 | 0.91 | MET (0.84) | METKDRRETKITPDGFRA | |
| SCHEMBL14748544 | 0.87 | MET (0.66) | METKDRRETKITPDGFRA | |
| SCHEMBL14742737 | 0.84 | MET (0.64) | METKDRRETKITPDGFRA | |
| SCHEMBL14747039 | 0.80 | AXL (0.71) | METKDRRETKITPDGFRA | |
| SCHEMBL14742929 | 0.78 | MET (0.71) | METKDRRETKITFLT3 | |
| SCHEMBL106402 | 0.76 | MET (0.74) | METKDRRETKITPDGFRA | |
| SCHEMBL139114 | 0.76 | MET (0.74) | METKDRRETKITPDGFRA | |
| SCHEMBL14746581 | 0.74 | MET (0.70) | METKDRRETKITPDGFRA | |
| SCHEMBL1729128 | 0.73 | MET (0.72) | METKDRRETKITPDGFRA | |
| SCHEMBL22766411 | 0.73 | AXL (0.61) | METKDRRETKITFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013032797-A2 | OXETANE 3,3-DICARBOXAMIDE COMPOUNDS AND METHODS OF MAKING AND USING SAME | NEW HOPE R & D BIOSCIENCE, INC. (US) | 2013-03-07 | — | — | WO | disclosed |
| WO-2013032797-A2 | OXETANE 3,3-DICARBOXAMIDE COMPOUNDS AND METHODS OF MAKING AND USING SAME | NEW HOPE R & D BIOSCIENCE, INC. (US) | 2013-03-07 | — | — | WO | disclosed |