Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10137831 | 0.87 | SMN1; SMN2 (0.67) | NAAANPC1RAB9AEPHX2HDAC3 | |
| SCHEMBL27512265 | 0.85 | NAAA (0.61) | NAAANPC1RAB9AEPHX2HDAC3 | |
| SCHEMBL7099696 | 0.84 | NAAA (0.59) | NAAANPC1RAB9AEPHX2HDAC3 | |
| SCHEMBL23996124 | 0.84 | HDAC3 (0.59) | NAAANPC1RAB9AEPHX2HDAC3 | |
| SCHEMBL14144651 | 0.84 | NAAA (0.59) | NAAANPC1RAB9AEPHX2HDAC3 | |
| SCHEMBL6579629 | 0.83 | NAAA (0.58) | NAAANPC1RAB9AEPHX2HDAC3 | |
| SCHEMBL12650598 | 0.82 | NAAA (0.66) | NAAANPC1RAB9AEPHX2HDAC3 | |
| SCHEMBL20362840 | 0.81 | RAB9A (0.64) | NAAANPC1RAB9AEPHX2HDAC3 | |
| SCHEMBL10099547 | 0.81 | NAAA (0.69) | NAAANPC1RAB9AEPHX2HDAC3 | |
| SCHEMBL8779817 | 0.80 | HDAC1 (0.79) | NAAANPC1RAB9AEPHX2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356356-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-2763554-A1 | NOVEL SUBSTITUTED CYCLOHEXANE COMPOUNDS | Takasago International Corporation (USA) (US) | 2014-08-13 | — | — | EP | disclosed |
| CN-103796535-A | Novel substituted cyclohexane compounds | TAKASAGO INTERNAT CORP USA | 2014-05-14 | — | — | CN | disclosed |
| WO-2013033501-A1 | NOVEL SUBSTITUTED CYCLOHEXANE COMPOUNDS | TAKASAGO INTERNATIONAL CORP. (USA) (US) | 2013-03-07 | — | — | WO | disclosed |