Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.41 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.41 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.41 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8459846 | 0.88 | LMNA (0.57) | TSHRCYP1A2LMNACYP2A6CES2 | |
| SCHEMBL703965 | 0.85 | ALDH1A1 (0.38) | TSHRLMNACYP2A6ALOX15L3MBTL1 | |
| SCHEMBL38902 | 0.82 | ALDH1A1 (0.40) | TSHRLMNACYP2A6CES2CES1 | |
| SCHEMBL38651919 | 0.78 | ALDH1A1 (0.38) | TSHRLMNACYP2A6ALOX15L3MBTL1 | |
| SCHEMBL10422510 | 0.78 | ALDH1A1 (0.38) | TSHRLMNACYP2A6ALOX15L3MBTL1 | |
| Ammonia Solution, Strong SCHEMBL3895204 | 0.78 | ALDH1A1 (0.38) | TSHRLMNACYP2A6ALOX15L3MBTL1 | |
| SCHEMBL11256956 | 0.78 | ALDH1A1 (0.38) | TSHRLMNACYP2A6ALOX15L3MBTL1 | |
| SCHEMBL11588969 | 0.78 | ALDH1A1 (0.38) | TSHRLMNACYP2A6ALOX15L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1400215 | 0.78 | ALDH1A1 (0.38) | TSHRLMNACYP2A6ALOX15L3MBTL1 | |
| SCHEMBL11589221 | 0.78 | ALDH1A1 (0.38) | TSHRLMNACYP2A6ALOX15L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114621279-A | Preparation method for aryl silane dimer compound through aryl silane self-coupling synthesis under photocatalysis | 湖南农业大学 | 2022-06-14 | — | — | CN | disclosed |
| CN-108727424-B | Organic compound, application thereof and organic electroluminescent device | 北京绿人科技有限责任公司 | 2020-10-02 | — | — | CN | disclosed |
| CN-110088112-A | Compound for electronic device | 默克专利有限公司 | 2019-08-02 | — | — | CN | disclosed |
| US-9233922-B2 | Process for producing N-(hetero)arylazoles | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2016-01-12 | — | — | US | disclosed |
| EP-2736881-B1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | TAKASAGO PERFUMERY CO LTD (JP) | 2015-10-07 | — | — | EP | disclosed |
| US-20140371461-A1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-12-18 | — | — | US | disclosed |
| EP-2736881-A1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | Takasago International Corporation (JP) | 2014-06-04 | — | — | EP | disclosed |
| WO-2013032035-A1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371461-A1 | PROCESS FOR PRODUCING N-(HETERO)ARYLAZOLES | CYP3A4, HCN4, PPOX | TSHR 3816/4885CYP1A2 64/4885LMNA 3840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.