Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.48 |
| ▸ | ICOSLG | O75144 | 1/20 | 0.48 |
| ▸ | ICOS | Q9Y6W8 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743545 | 0.89 | CHUK (0.46) | CHUKICOSLGICOSNPY2RRAB9A | |
| SCHEMBL14743310 | 0.84 | MEN1 (0.52) | RAB9AKMT2ANPC1MEN1HPGD | |
| SCHEMBL14744028 | 0.83 | GRM4 (0.53) | — | |
| SCHEMBL14743483 | 0.83 | POLB (0.37) | RAB9ANPC1POLBALDH1A1SMN1; SMN2 | |
| SCHEMBL14743690 | 0.82 | KDM4C (0.47) | RAB9AKMT2ANPC1MEN1CA1 | |
| SCHEMBL14743792 | 0.81 | KMT2A (0.48) | RAB9AKMT2ANPC1MEN1HPGD | |
| SCHEMBL14742999 | 0.80 | KDM4C (0.45) | KMT2AMEN1GLSPOLBHTT | |
| SCHEMBL14743835 | 0.79 | MEN1 (0.43) | KMT2ANPC1MEN1HPGDPOLB | |
| SCHEMBL14743367 | 0.77 | GAA (0.55) | RAB9AKMT2ANPC1MEN1HPGD | |
| SCHEMBL14743648 | 0.77 | PYGL (0.52) | RAB9AKMT2ANPC1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | claimed |
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |