Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
| ▸ | ICOSLG | O75144 | 1/20 | 0.46 |
| ▸ | ICOS | Q9Y6W8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743443 | 0.89 | CHUK (0.48) | CHUKICOSLGICOSHTTPOLB | |
| SCHEMBL14743294 | 0.84 | POLB (0.55) | HTTPOLBRAB9ANPC1KMT2A | |
| SCHEMBL14744244 | 0.83 | MAPK8 (0.49) | HTTPOLBRAB9ANPC1KMT2A | |
| SCHEMBL14743750 | 0.82 | HTT (0.47) | HTTPOLBRAB9ANPC1KMT2A | |
| SCHEMBL14743078 | 0.81 | HTT (0.50) | HTTPOLBNPC1KMT2AALDH1A1 | |
| SCHEMBL14743578 | 0.81 | RORC (0.44) | HTTPOLBKMT2AALDH1A1KDM4E | |
| SCHEMBL14744260 | 0.78 | SMN1; SMN2 (0.55) | RAB9ANPC1KMT2AALDH1A1KDM4E | |
| SCHEMBL14742913 | 0.77 | RAB9A (0.49) | RAB9AKMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL14744254 | 0.76 | POLB (0.49) | HTTPOLBRAB9ANPC1KMT2A | |
| SCHEMBL14743107 | 0.76 | LMNA (0.49) | CHUKICOSLGICOSPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |