Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743471 | 0.85 | PYGL (0.49) | PYGLRAB9AKMT2ANPC1HPGD | |
| SCHEMBL14743159 | 0.82 | PYGL (0.53) | PYGLHPGDPDK1ALDH1A1KDM4E | |
| SCHEMBL14743689 | 0.82 | PYGL (0.47) | PYGLRAB9AKMT2ANPC1NTRK1 | |
| SCHEMBL14743792 | 0.82 | KMT2A (0.48) | RAB9AKMT2ANPC1HPGDTDP1 | |
| SCHEMBL14743443 | 0.77 | CHUK (0.48) | RAB9AKMT2ANPC1HPGDMEN1 | |
| SCHEMBL14743950 | 0.76 | PYGL (0.46) | PYGLRAB9AKMT2AHPGDMEN1 | |
| SCHEMBL14744301 | 0.75 | AGTR1 (0.49) | RAB9AKMT2ANPC1HPGDCYP1A2 | |
| SCHEMBL14743750 | 0.74 | HTT (0.47) | RAB9AKMT2ANPC1HPGDCYP1A2 | |
| SCHEMBL14744028 | 0.73 | GRM4 (0.53) | PYGL | |
| SCHEMBL14743409 | 0.72 | OPRK1 (0.46) | RAB9AKMT2ANPC1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | claimed |
| WO-2013030358-A1 | GLYCINE B ANTAGONISTS | MERZ PHARMA GMBH & CO. KGAA (DE) | 2013-03-07 | — | — | WO | disclosed |