Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 8/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743954 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL17232237 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL25749303 | 0.88 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL22930076 | 0.85 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL6722519 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL6722516 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL6719127 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL1763873 | 0.84 | CYP1A2 (0.49) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL1317487 | 0.84 | CYP1A2 (0.49) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL15418649 | 0.84 | CYP1A2 (0.49) | SMN1; SMN2CYP1A2CYP2C9CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107253968-B | Universal and stereospecific synthesis of gamma, delta-unsaturated amino acids by Wittig reaction | 国家科学研究中心 | 2020-03-13 | — | — | CN | disclosed |
| EP-2751124-B1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NAT RECH SCIENT (FR) | 2018-05-16 | — | — | EP | disclosed |
| CN-107253968-A | Pass through the γ of witig reaction, the general and stereoselectivesynthesis of δ unsaturation amino acid | 国家科学研究中心 | 2017-10-17 | — | — | CN | disclosed |
| US-9242925-B2 | Versatile and stereospecific synthesis of γ,δ-unsaturated amino acids by Wittig reaction | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2016-01-26 | — | — | US | disclosed |
| US-20140364339-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2014-12-11 | — | — | US | disclosed |
| EP-2751124-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | Centre National de la Recherche Scientifique (CNRS) (FR) | 2014-07-09 | — | — | EP | disclosed |
| CN-103889994-A | Universal and stereospecific synthesis of gamma-unsaturated amino acids by Wittig reaction | CENTRE NAT RECH SCIENT | 2014-06-25 | — | — | CN | disclosed |
| WO-2013030193-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364339-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | BCAT1, BCAT2, ALAD | SMN1; SMN2 3088/4885CYP1A2 156/4885CYP2C9 252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.