Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994720 | 0.86 | MEN1 (0.56) | GPR35ALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL887770 | 0.86 | GPR35 (0.77) | GPR35ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL17132338 | 0.80 | ALDH1A1 (0.62) | GPR35ALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL10639224 | 0.80 | GPR35 (0.69) | GPR35ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL5933778 | 0.80 | GPR35 (0.69) | GPR35ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL28683782 | 0.80 | ALDH1A1 (0.72) | GPR35ALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL8329477 | 0.78 | GPR35 (0.66) | GPR35ALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL2165473 | 0.78 | GPR35 (1.00) | GPR35ALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL30807397 | 0.78 | GPR35 (1.00) | GPR35ALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL5500088 | 0.77 | ALDH1A1 (0.67) | GPR35ALDH1A1CYP3A4KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |