Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744364 | 0.87 | ALDH1A1 (0.49) | LMNAALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL10759014 | 0.87 | LMNA (0.48) | LMNAALDH1A1HTTHDAC1HDAC8 | |
| SCHEMBL10755015 | 0.79 | LMNA (0.50) | LMNAALDH1A1HTTRORCKDM4E | |
| SCHEMBL9813753 | 0.78 | HDAC1 (0.64) | LMNAAKR1B1ALDH1A1HTTTSHR | |
| SCHEMBL10581074 | 0.77 | HDAC1 (0.58) | LMNAAKR1B1ALDH1A1HTTTSHR | |
| SCHEMBL1128420 | 0.77 | KCNH2 (0.51) | LMNAALDH1A1HTTTSHRHSD17B10 | |
| SCHEMBL26978769 | 0.77 | LMNA (0.56) | LMNAALDH1A1GAAL3MBTL1TDP1 | |
| SCHEMBL31277779 | 0.76 | TSHR (0.50) | LMNAALDH1A1HTTTSHRL3MBTL1 | |
| SCHEMBL23193744 | 0.75 | ALDH1A1 (0.64) | ALDH1A1HTTHSD17B10RORCKDM4E | |
| SCHEMBL163450 | 0.75 | HTT (0.51) | LMNAAKR1B1ALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |