Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503563 | 0.89 | GAA (0.47) | TSHRPSIP1LMNAALDH1A1CA1 | |
| SCHEMBL10758725 | 0.85 | TDP1 (0.46) | TSHRLMNAALDH1A1CA1CA2 | |
| SCHEMBL10758730 | 0.82 | LMNA (0.46) | TSHRPSIP1LMNAALDH1A1CA1 | |
| SCHEMBL15186464 | 0.81 | TSHR (0.54) | TSHRPSIP1LMNAALDH1A1CA1 | |
| SCHEMBL10755015 | 0.80 | LMNA (0.50) | LMNAALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL1621831 | 0.79 | CA2 (0.55) | TSHRCA1CA2CA9CA12 | |
| SCHEMBL1623066 | 0.79 | TSHR (0.52) | TSHRALDH1A1CA1CA2CA9 | |
| SCHEMBL1623314 | 0.79 | TSHR (0.52) | TSHRLMNAALDH1A1CA1CA2 | |
| SCHEMBL5859628 | 0.79 | PSIP1 (0.56) | PSIP1LMNAALDH1A1HSD11B1HTT | |
| SCHEMBL18631331 | 0.78 | TSHR (0.50) | TSHRLMNAALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118922406-A | Synthesis of KIF18A inhibitors | 安进公司 | 2024-11-08 | — | — | CN | disclosed |