Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | MAP2 | P11137 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 2/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR1E | P28566 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30321020 | 0.88 | RORC (0.45) | PLA2G7GRIN2BMAP2ALOX5APFEN1 | |
| SCHEMBL14744245 | 0.88 | RORC (0.45) | PLA2G7GRIN2BMAP2ALOX5APFEN1 | |
| SCHEMBL14744202 | 0.79 | RORC (0.50) | MAP2RORC | |
| SCHEMBL30320910 | 0.79 | RORC (0.50) | MAP2RORC | |
| SCHEMBL5175734 | 0.79 | RORC (0.42) | RORCHTR1AHTR1DHTR1BHTR2A | |
| SCHEMBL14744501 | 0.79 | ALOX5AP (0.43) | GRIN2BMAP2ALOX5APFEN1SCN10A | |
| SCHEMBL30026839 | 0.78 | PLA2G7 (0.45) | PLA2G7RORCPOLBNPSR1HTR1A | |
| SCHEMBL24032682 | 0.78 | POLB (0.62) | ALOX5APFEN1PDK2SCN10ARORC | |
| SCHEMBL30320923 | 0.78 | POLB (0.62) | ALOX5APFEN1PDK2SCN10ARORC | |
| SCHEMBL1555931 | 0.78 | CYP3A4 (0.46) | GRIN2BPOLBHTR2ACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |