Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.66 |
| ▸ | PNLIP | P16233 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20572668 | 0.82 | RAB9A (0.56) | RORC | |
| SCHEMBL14746610 | 0.81 | RORC (0.53) | RORC | |
| Fluoride SCHEMBL11789657 | 0.81 | EPHX2 (0.54) | RORCPNLIP | |
| SCHEMBL19200766 | 0.81 | RORC (0.53) | RORCPNLIP | |
| SCHEMBL20943241 | 0.80 | RORC (1.00) | RORC | |
| SCHEMBL18281383 | 0.80 | RORC (0.64) | RORC | |
| SCHEMBL3375982 | 0.79 | RORC (0.58) | RORC | |
| SCHEMBL21245435 | 0.78 | RORC (0.83) | RORC | |
| SCHEMBL20590952 | 0.78 | CYP3A4 (0.54) | RORC | |
| SCHEMBL20572878 | 0.78 | CYP3A4 (0.54) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |