Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 16/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746610 | 0.82 | RORC (0.53) | RORCSLC22A12CYP2C9CYP2C19 | |
| SCHEMBL14744265 | 0.81 | RORC (0.66) | RORCPNLIP | |
| SCHEMBL3375982 | 0.80 | RORC (0.58) | RORCSLC22A12CYP2C9CYP2C19 | |
| SCHEMBL19199851 | 0.76 | RORC (0.47) | RORC | |
| SCHEMBL30321020 | 0.75 | RORC (0.45) | RORC | |
| SCHEMBL14744245 | 0.75 | RORC (0.45) | RORC | |
| SCHEMBL14746825 | 0.74 | ACLY (0.41) | RORCSLC22A12 | |
| SCHEMBL20572668 | 0.73 | RAB9A (0.56) | RORCCYP2C19 | |
| SCHEMBL19199772 | 0.73 | RORC (0.41) | RORCSLC22A12 | |
| SCHEMBL14746593 | 0.72 | HSD17B10 (0.45) | RORCCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019022235-A1 | THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR ALOPECIA AREATA | 東レ株式会社 | 2019-01-31 | — | — | WO | disclosed |
| WO-2019022234-A1 | INFLAMMATORY BOWEL DISEASE THERAPEUTIC AGENT OR PROPHYLACTIC AGENT | 東レ株式会社 | 2019-01-31 | — | — | WO | disclosed |
| WO-2017131156-A1 | CYCLIC AMINE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 | 2017-08-03 | — | — | WO | disclosed |