Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.52 |
| ▸ | PTPRC | P08575 | 3/20 | 0.45 |
| ▸ | S100A4 | P26447 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746841 | 0.90 | PTGS2 (0.50) | CYP19A1CYP11B1CYP11B2PTPRCS100A4 | |
| SCHEMBL14746632 | 0.87 | CYP11B1 (0.54) | CYP19A1CYP11B1CYP11B2PTPRCS100A4 | |
| SCHEMBL14744533 | 0.87 | RORC (0.49) | CYP19A1CYP11B1CYP11B2PTPRCS100A4 | |
| SCHEMBL14747059 | 0.85 | CYP19A1 (0.40) | CYP19A1CYP11B1CYP11B2PTPRCS100A4 | |
| SCHEMBL14743965 | 0.83 | PTPRC (0.42) | CYP19A1CYP11B1CYP11B2PTPRCS100A4 | |
| SCHEMBL14746823 | 0.82 | PTPRC (0.44) | CYP19A1CYP11B1CYP11B2PTPRCS100A4 | |
| SCHEMBL14744512 | 0.81 | RORC (0.50) | CYP19A1PTPRCS100A4BCHEACHE | |
| SCHEMBL14746840 | 0.81 | PTPRC (0.40) | CYP19A1CYP11B1CYP11B2PTPRCS100A4 | |
| SCHEMBL14744310 | 0.81 | PTPRC (0.42) | CYP19A1CYP11B1CYP11B2PTPRCS100A4 | |
| SCHEMBL14746814 | 0.80 | RORC (0.52) | PTPRCS100A4BCHEACHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |