Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.42 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | BAX | Q07812 | 2/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746823 | 0.86 | PTPRC (0.44) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL14744328 | 0.81 | CYP19A1 (0.52) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL14746632 | 0.80 | CYP11B1 (0.54) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL14746841 | 0.80 | PTGS2 (0.50) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL14744238 | 0.80 | PTPRC (0.40) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL14746789 | 0.79 | PTPRC (0.39) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL14744512 | 0.79 | RORC (0.50) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL14744533 | 0.77 | RORC (0.49) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL14744240 | 0.77 | HSPB1 (0.47) | PTPRCS100A4BCHEACHECES1 | |
| SCHEMBL14746568 | 0.77 | SCN10A (0.45) | PTPRCS100A4BCHEACHECES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |