Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetophenone SCHEMBL28081296 | 0.93 | ALDH1A1 (0.54) | CES2MAPTLMNAPOLBHTT | |
| SCHEMBL9489732 | 0.90 | SRD5A2 (0.54) | MAPTLMNAPOLBHTTALDH1A1 | |
| SCHEMBL2921288 | 0.88 | LMNA (0.59) | CES2MAPTLMNAPOLBHTT | |
| Methyl Alcohol SCHEMBL28094568 | 0.85 | LMNA (0.56) | CES2MAPTLMNAPOLBHTT | |
| SCHEMBL5313439 | 0.83 | MAPT (0.60) | CES2MAPTLMNAPOLBHTT | |
| SCHEMBL11010668 | 0.83 | LMNA (0.60) | CES2MAPTLMNAPOLBHTT | |
| SCHEMBL27497022 | 0.83 | GAA (0.60) | CES2MAPTLMNAPOLBHTT | |
| SCHEMBL29355334 | 0.83 | CES2 (0.75) | CES2MAPTLMNAPOLBHTT | |
| SCHEMBL11230405 | 0.83 | CES2 (0.75) | CES2MAPTLMNAPOLBHTT | |
| SCHEMBL28144535 | 0.82 | CES2 (0.51) | CES2MAPTLMNAPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108463108-A | Active material is used to prevent the purposes of plant virus infection | 拜耳作物科学股份公司 | 2018-08-28 | — | — | CN | claimed |
| CN-108117518-A | N-2,4- substituted-phenyl bisamide class compounds and preparation method and application | 湖南化工研究院有限公司 | 2018-06-05 | — | — | CN | claimed |
| CN-108117529-A | N- phenyl thiazole amides compounds and preparation method and application | 湖南化工研究院有限公司 | 2018-06-05 | — | — | CN | claimed |
| CN-102834116-B | The treatment of WNT/ FZ relevant disease | DUKE UNIVERSITY (US) | 2015-09-16 | — | — | CN | claimed |
| CN-103547565-A | Substituted cyanoaniline compounds, preparation and use thereof | SINOCHEM CORP | 2014-01-29 | — | — | CN | claimed |
| CN-86102202-A | The preparation method of the chrysomelid genus of bar larva agent for killing | — | 1986-10-01 | — | — | CN | claimed |
| CN-108484601-B | Contain the benzothiazine -4- ketone compounds and preparation method thereof of 2,8- diaza spiro [4.5] decane segment | 浙江司太立制药股份有限公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-110088102-A | A kind of nitrogen-containing hetero cyclics, preparation method, pharmaceutical composition and application | 罗欣药业(上海)有限公司 | 2019-08-02 | — | — | CN | disclosed |
| CN-109890822-A | INHIBITORS OF CELLULAR METABOLIC PROCESSES | 安吉奥斯医药品有限公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-109476596-A | Organic electronic element compound, organic electronic element and its electronic device using the compound | 德山新勒克斯有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-108738320-A | 4- amino -2- (1H- pyrazolos [3 as the cGMP conditioning agents for treating angiocardiopathy, 4-b] pyridin-3-yl) -6- oxos -6,7- dihydro -5H- pyrrolo-es [2,3-d] pyrimidine derivatives and respective (1H- indazole -3- bases) derivative | 默沙东公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-108484601-A | Benzothiazine -4- ketone compounds and preparation method thereof containing 2,8- diaza spiros [4.5] decane segment | 浙江司太立制药股份有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-108474981-A | Aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal indicate element | 日产化学工业株式会社 | 2018-08-31 | — | — | CN | disclosed |
| CN-103429079-A | Histone deacetylase inhibitors and compositions and methods of use thereof | CHDI FOUNDATION INC | 2013-12-04 | — | — | CN | disclosed |
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |
| CN-102753555-A | Macrocycles as factor XIA inhibitors | BRISTOL MYERS SQUIBB CO | 2012-10-24 | — | — | CN | disclosed |
| CN-1012786-B | The chrysomelid genus of bar kills young agent | LILLY CO ELI (US) | 1991-06-12 | — | — | CN | disclosed |
| CN-1012786-B | The chrysomelid genus of bar kills young agent | LILLY CO ELI (US) | 1991-06-12 | — | — | CN | disclosed |
| CN-86102202-A | The preparation method of the chrysomelid genus of bar larva agent for killing | — | 1986-10-01 | — | — | CN | disclosed |
| CN-86102202-A | The preparation method of the chrysomelid genus of bar larva agent for killing | — | 1986-10-01 | — | — | CN | disclosed |