Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.37 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6112961 | 0.80 | ALDH1A1 (0.58) | HPGDALDH1A1TDP1NPC1RECQL | |
| SCHEMBL29469206 | 0.80 | ALDH1A1 (0.58) | HPGDALDH1A1TDP1NPC1RECQL | |
| SCHEMBL28024174 | 0.79 | HPGD (0.61) | HPGDALDH1A1TDP1NPC1RECQL | |
| SCHEMBL29804797 | 0.75 | HSPB1 (0.45) | HPGDALDH1A1TDP1NPC1RECQL | |
| SCHEMBL1459508 | 0.75 | GPR35 (0.49) | HPGDALDH1A1TDP1NPC1RECQL | |
| SCHEMBL18663645 | 0.75 | HSPB1 (0.45) | HPGDALDH1A1TDP1NPC1RECQL | |
| SCHEMBL14746593 | 0.75 | HSD17B10 (0.45) | HPGDALDH1A1NPC1RAB9AS100A4 | |
| SCHEMBL14746574 | 0.75 | HSD17B10 (0.45) | HPGDALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL14744548 | 0.74 | MPL (0.41) | ALDH1A1POLBL3MBTL1 | |
| SCHEMBL27843148 | 0.74 | TDP1 (0.58) | ALDH1A1TDP1NPC1RECQLRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |