Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.45 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30695897 | 0.82 | MAPT (0.58) | MAPTPKMNPSR1SMN1; SMN2KMT2A | |
| SCHEMBL14988537 | 0.82 | MAPT (0.58) | MAPTPKMNPSR1SMN1; SMN2KMT2A | |
| SCHEMBL14988486 | 0.80 | HSPB1 (0.48) | MAPTPKMNPSR1SMN1; SMN2HSPB1 | |
| SCHEMBL14988521 | 0.79 | ALDH1A1 (0.43) | ALOX5APFEN1MAPTNPSR1SMN1; SMN2 | |
| SCHEMBL14988356 | 0.78 | MAPT (0.45) | ALOX5APFEN1MAPTPKMNPSR1 | |
| SCHEMBL14746823 | 0.78 | PTPRC (0.44) | ALOX5APFEN1MAPTNPSR1ABL1 | |
| SCHEMBL14988769 | 0.77 | EIF4A1 (0.48) | MAPTPKMNPSR1SMN1; SMN2HSPB1 | |
| SCHEMBL14744065 | 0.77 | ALDH1A1 (0.41) | ALOX5APFEN1MAPTPKMNPSR1 | |
| SCHEMBL3173477 | 0.77 | KMT2A (0.55) | ALOX5APFEN1MAPTSMN1; SMN2HSPB1 | |
| SCHEMBL29791390 | 0.77 | KMT2A (0.55) | ALOX5APFEN1MAPTSMN1; SMN2HSPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |