Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 13/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31729824 | 0.87 | GRM2 (0.41) | CYP2C9CYP2D6KCNH2GPR142SCN9A | |
| SCHEMBL14744477 | 0.83 | ALOX5AP (0.46) | ALOX5APFEN1SCN9AS1PR1TRPA1 | |
| SCHEMBL14744308 | 0.79 | ALOX5AP (0.45) | ALOX5APFEN1SCN9AS1PR1TRPA1 | |
| SCHEMBL14743932 | 0.78 | RORC (0.48) | ALOX5APFEN1SCN9AS1PR1TRPA1 | |
| SCHEMBL14746755 | 0.75 | RORC (0.54) | ALOX5APFEN1SCN9APDK2 | |
| SCHEMBL14744102 | 0.74 | RORC (0.49) | ALOX5APFEN1CYP2C9SCN9AS1PR1 | |
| SCHEMBL14746770 | 0.74 | SCN10A (0.50) | ALOX5APFEN1SCN9AS1PR1 | |
| SCHEMBL31729829 | 0.72 | GLA (0.43) | PDK2S1PR1 | |
| SCHEMBL24032682 | 0.71 | POLB (0.62) | ALOX5APFEN1SCN9APDK2S1PR1 | |
| SCHEMBL1492639 | 0.71 | DYRK1A (0.49) | CYP2C9CYP2D6S1PR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |