Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744512 | 0.80 | RORC (0.50) | RORCCYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL14746770 | 0.77 | SCN10A (0.50) | S1PR1ALOX5APFEN1SCN10ASCN9A | |
| SCHEMBL14743932 | 0.75 | RORC (0.48) | RORCS1PR1ALOX5APFEN1SCN10A | |
| SCHEMBL14744456 | 0.74 | ALOX5AP (0.45) | CYP2C9S1PR1ALOX5APFEN1SCN9A | |
| SCHEMBL14744206 | 0.74 | PLA2G7 (0.45) | RORCALOX5APFEN1SCN10ASCN9A | |
| SCHEMBL24032682 | 0.74 | POLB (0.62) | RORCS1PR1ALOX5APFEN1SCN10A | |
| SCHEMBL14744245 | 0.74 | RORC (0.45) | RORCALOX5APFEN1SCN10ASCN9A | |
| SCHEMBL30321020 | 0.74 | RORC (0.45) | RORCALOX5APFEN1SCN10ASCN9A | |
| SCHEMBL30320923 | 0.74 | POLB (0.62) | RORCS1PR1ALOX5APFEN1SCN10A | |
| SCHEMBL14744477 | 0.73 | ALOX5AP (0.46) | RORCS1PR1ALOX5APFEN1SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |