Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 5/20 | 0.45 |
| ▸ | FEN1 | P39748 | 5/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744477 | 0.88 | ALOX5AP (0.46) | ALOX5APFEN1SCN9ATRPA1SCN10A | |
| SCHEMBL14743932 | 0.83 | RORC (0.48) | ALOX5APFEN1SCN9ATRPA1SCN10A | |
| SCHEMBL14746840 | 0.81 | PTPRC (0.40) | ALOX5APFEN1ABL1RORC | |
| SCHEMBL14744456 | 0.79 | ALOX5AP (0.45) | ALOX5APFEN1SCN9ATRPA1S1PR1 | |
| SCHEMBL14746755 | 0.78 | RORC (0.54) | ALOX5APFEN1SCN9ASCN10ARORC | |
| SCHEMBL529353 | 0.73 | IMPDH2 (0.51) | ALOX5APFEN1FYNABL1 | |
| SCHEMBL14744102 | 0.72 | RORC (0.49) | ALOX5APFEN1SCN9ASCN10ARORC | |
| SCHEMBL14746770 | 0.71 | SCN10A (0.50) | ALOX5APFEN1SCN9ASCN10AS1PR1 | |
| SCHEMBL24032682 | 0.71 | POLB (0.62) | ALOX5APFEN1SCN9ATRPA1SCN10A | |
| SCHEMBL14744206 | 0.71 | PLA2G7 (0.45) | ALOX5APFEN1SCN9ATRPA1SCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |