Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14738846 | 0.92 | DGAT1 (0.32) | DGAT1CNR1 | |
| SCHEMBL14743870 | 0.90 | DGAT1 (0.32) | DGAT1 | |
| SCHEMBL14738845 | 0.83 | SYK (0.35) | DGAT1 | |
| SCHEMBL14738054 | 0.82 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL14744385 | 0.81 | MAPT (0.33) | DGAT1 | |
| SCHEMBL14746970 | 0.80 | HCAR2 (0.33) | DGAT1 | |
| SCHEMBL14737449 | 0.79 | JAK2 (0.41) | DGAT1CNR1 | |
| SCHEMBL14744226 | 0.79 | SYK (0.34) | DGAT1 | |
| SCHEMBL14738342 | 0.77 | SYK (0.43) | DGAT1 | |
| SCHEMBL14737439 | 0.77 | MAPK1 (0.32) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2763990-A1 | PYRROLOPYRAZINE KINASE INHIBITORS | F.HOFFMANN-LA ROCHE AG (CH) | 2014-08-13 | — | — | EP | disclosed |
| WO-2013030138-A1 | PYRROLOPYRAZINE KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2013-03-07 | — | — | WO | disclosed |