SCHEMBL14744985

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31287796	1.00	ALOX5 (0.50)	ALOX5GRM5PRMT5MEN1KMT2A
	SCHEMBL29666622	0.91	NUDT1 (0.48)	ALOX5GRM5PRMT5MEN1KMT2A
	SCHEMBL23531939	0.90	MAOB (0.50)	ALOX5PRMT5MEN1KMT2ACYP3A4
	SCHEMBL8550828	0.90	ALOX5 (0.56)	ALOX5PRMT5MEN1KMT2ACYP3A4
	SCHEMBL2521216	0.89	ALOX5 (0.60)	ALOX5MEN1KMT2ANUDT1CYP3A4
	SCHEMBL8773184	0.89	MAOB (0.51)	ALOX5GRM5PRMT5NUDT1LMNA
	SCHEMBL31287990	0.89	MAOB (0.51)	ALOX5GRM5PRMT5NUDT1LMNA
	SCHEMBL18864590	0.89	MAOB (0.51)	ALOX5PRMT5MEN1KMT2ACYP3A4
	SCHEMBL30522847	0.89	MAOB (0.51)	ALOX5PRMT5MEN1KMT2ACYP3A4
	SCHEMBL20765124	0.85	ALOX5 (0.43)	ALOX5GRM5PRMT5MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.