Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17597160 | 0.96 | — | — | |
| SCHEMBL17597161 | 0.91 | — | — | |
| SCHEMBL17597159 | 0.87 | CDC7 (0.33) | CDC7 | |
| SCHEMBL14745774 | 0.87 | CDC7 (0.33) | CDC7 | |
| SCHEMBL14740909 | 0.76 | CDC7 (0.41) | CDC7PDE3BPDE3A | |
| SCHEMBL14740945 | 0.76 | KMO (0.43) | PDE3BPDE3A | |
| SCHEMBL14757794 | 0.75 | CA2 (0.40) | CDC7PDE3BPDE3A | |
| SCHEMBL14757852 | 0.75 | CA2 (0.40) | PDE3BPDE3A | |
| SCHEMBL14745239 | 0.75 | PDE3B (0.43) | PDE3BPDE3A | |
| SCHEMBL14741298 | 0.73 | KMO (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750504-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC Therapeutics, Inc. (US) | 2014-07-09 | — | — | EP | claimed |
| WO-2013033258-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2013-03-07 | — | — | WO | claimed |