Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746158 | 0.93 | MAPT (0.34) | MRGPRX4MAPTALDH1A1L3MBTL1RORC | |
| SCHEMBL14746159 | 0.91 | MRGPRX4 (0.36) | MRGPRX4MAPTEDNRBALDH1A1L3MBTL1 | |
| SCHEMBL14745493 | 0.77 | ALDH1A1 (0.39) | MAPTALDH1A1L3MBTL1LMNAKMT2A | |
| SCHEMBL14745618 | 0.77 | ALDH1A1 (0.42) | MRGPRX4MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL14745278 | 0.76 | IP6K1 (0.42) | MRGPRX4MAPTALDH1A1L3MBTL1RORC | |
| SCHEMBL14745700 | 0.76 | ALDH1A1 (0.34) | MAPTALDH1A1L3MBTL1DCTPP1LMNA | |
| SCHEMBL14745683 | 0.76 | HIF1A (0.42) | MRGPRX4MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL14745963 | 0.76 | GRK6 (0.43) | MRGPRX4MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL14747050 | 0.76 | MRGPRX4 (0.44) | MRGPRX4MAPTALDH1A1L3MBTL1LMNA | |
| SCHEMBL14745697 | 0.75 | MRGPRX4 (0.44) | MRGPRX4MAPTALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750505-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC Therapeutics, Inc. (US) | 2014-07-09 | — | — | EP | claimed |
| WO-2013033240-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2013-03-07 | — | — | WO | claimed |