Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746157 | 0.93 | MRGPRX4 (0.35) | MAPTRORCDCTPP1THRBMRGPRX4 | |
| SCHEMBL14746159 | 0.85 | MRGPRX4 (0.36) | MAPTRORCDCTPP1THRBMRGPRX4 | |
| SCHEMBL17594864 | 0.76 | ALDH1A1 (0.39) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL14745703 | 0.72 | — | — | |
| SCHEMBL14745493 | 0.71 | ALDH1A1 (0.39) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL14745495 | 0.71 | ALDH1A1 (0.33) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL14745618 | 0.70 | ALDH1A1 (0.42) | MAPTMRGPRX4ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL14745278 | 0.70 | IP6K1 (0.42) | MAPTRORCMRGPRX4PARP1ALDH1A1 | |
| SCHEMBL14745700 | 0.70 | ALDH1A1 (0.34) | MAPTDCTPP1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL14745683 | 0.69 | HIF1A (0.42) | MAPTMRGPRX4ALDH1A1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750505-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC Therapeutics, Inc. (US) | 2014-07-09 | — | — | EP | claimed |
| WO-2013033240-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2013-03-07 | — | — | WO | claimed |