Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 5/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | CCR6 | P51684 | 4/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.30 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16373781 | 0.88 | LIPE (0.39) | LIPECNR2EGFRCXCR2LPL | |
| SCHEMBL23057745 | 0.82 | LIPE (0.33) | LIPECXCR2LPLLIPG | |
| SCHEMBL29973522 | 0.82 | LIPE (0.33) | LIPECXCR2LPLLIPG | |
| SCHEMBL16282205 | 0.81 | EGFR (0.47) | LIPEEGFRTRPV4SLC6A4KCNH2 | |
| SCHEMBL25368001 | 0.81 | SNCA (0.38) | LIPECXCR2CCR6KCNH2 | |
| SCHEMBL25092921 | 0.80 | EGFR (0.37) | LIPEEGFRLPLLIPGTRPV4 | |
| SCHEMBL22338002 | 0.80 | EGFR (0.37) | LIPEEGFRLPLLIPGTRPV4 | |
| SCHEMBL15912491 | 0.80 | LPL (0.38) | LIPECXCR2LPLLIPG | |
| SCHEMBL29276160 | 0.79 | EGFR (0.35) | LIPEEGFRLPLLIPGTRPV4 | |
| SCHEMBL31713106 | 0.79 | HRH4 (0.39) | LIPECXCR2TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |