Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1C | Q13936 | 3/20 | 0.66 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.66 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.66 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | DHFR | P00374 | 2/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10113069 | 0.88 | CACNA1F (0.67) | CACNA1CCACNA1FCACNA1DCACNA1SADORA2B | |
| SCHEMBL7694814 | 0.78 | DHFR (0.67) | CACNA1CCACNA1FCACNA1DCACNA1SALDH1A1 | |
| SCHEMBL7690975 | 0.76 | ALDH1A1 (0.64) | CACNA1CCACNA1FCACNA1DCACNA1SALDH1A1 | |
| SCHEMBL7695444 | 0.76 | ALDH1A1 (1.00) | ALDH1A1ALOX12ADORA2BMAPTTDP1 | |
| SCHEMBL7693397 | 0.76 | MAPT (0.64) | CACNA1CCACNA1FCACNA1DCACNA1SALDH1A1 | |
| SCHEMBL10789349 | 0.75 | CACNA1F (0.67) | CACNA1CCACNA1FCACNA1DCACNA1STP53 | |
| SCHEMBL14164087 | 0.75 | CA1 (0.78) | ALDH1A1CA1CA2DHFRADORA2B | |
| SCHEMBL10113419 | 0.75 | CA1 (1.00) | ALDH1A1ALOX12CA1CA2DHFR | |
| SCHEMBL10471492 | 0.74 | CACNA1C (0.60) | CACNA1CCACNA1FCACNA1DCACNA1SALDH1A1 | |
| SCHEMBL27673360 | 0.73 | CACNA1C (0.64) | CACNA1CCACNA1FCACNA1DCACNA1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389529-B2 | Methods and compositions for treating asthma | HYDRA BIOSCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389529-B2 | Methods and compositions for treating asthma | HYDRA BIOSCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |