Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.61 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.61 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.61 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.61 |
| ▸ | DHFR | P00374 | 1/20 | 0.60 |
| ▸ | GUSB | P08236 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA2 | P00918 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA7 | P43166 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28555966 | 0.88 | DHFR (0.77) | ALDH1A1ALOX12DHFRGUSBCA1 | |
| SCHEMBL7694814 | 0.86 | DHFR (0.67) | MAPTALDH1A1ALOX12CACNA1FCACNA1D | |
| SCHEMBL7690939 | 0.85 | CA1 (0.65) | MAPTALDH1A1ALOX12DHFRCA1 | |
| SCHEMBL7697739 | 0.84 | GUSB (0.64) | MAPTALDH1A1ALOX12DHFRGUSB | |
| SCHEMBL10113372 | 0.84 | ADORA2B (0.67) | ALDH1A1DHFRGUSBCA1CA2 | |
| SCHEMBL31541530 | 0.84 | CA1 (0.79) | MAPTALDH1A1ALOX12CACNA1DDHFR | |
| SCHEMBL7695461 | 0.83 | ALDH1A1 (0.57) | MAPTALDH1A1ALOX12DHFRGUSB | |
| SCHEMBL31541537 | 0.83 | GUSB (0.64) | MAPTALDH1A1ALOX12DHFRGUSB | |
| SCHEMBL31541585 | 0.82 | GUSB (0.63) | ALDH1A1ALOX12DHFRGUSBCA1 | |
| SCHEMBL7688881 | 0.82 | DHFR (0.64) | ALDH1A1ALOX12DHFRGUSBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | claimed |
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |