Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 5/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12971902 | 0.77 | KDM1A (0.61) | SLC6A2MAOAKDM1ASMN1; SMN2TRPV1 | |
| SCHEMBL14747497 | 0.74 | TAS1R3 (0.46) | SLC6A2MAOAKDM1AEPHX2SMN1; SMN2 | |
| SCHEMBL14747476 | 0.73 | CYP1A2 (0.43) | MAOAKDM1AEPHX2KMT2AMAOB | |
| SCHEMBL12976288 | 0.73 | KDM1A (0.46) | SLC6A2MAOAKDM1ASMN1; SMN2TRPV1 | |
| SCHEMBL14747464 | 0.72 | KDM1A (0.46) | MAOAKDM1AEPHX1EPHX2SMN1; SMN2 | |
| SCHEMBL2778217 | 0.69 | FFAR1 (0.48) | SLC6A2MAOAEPHX2SMN1; SMN2TRPV1 | |
| SCHEMBL2778214 | 0.69 | FFAR1 (0.48) | SLC6A2MAOAEPHX2SMN1; SMN2TRPV1 | |
| SCHEMBL2774128 | 0.69 | SLC6A2 (0.60) | SLC6A2SMN1; SMN2TRPV1HPGDNPC1 | |
| SCHEMBL2774127 | 0.69 | SLC6A2 (0.60) | SLC6A2SMN1; SMN2TRPV1HPGDNPC1 | |
| SCHEMBL12971973 | 0.68 | PTGIR (0.42) | SLC6A2MAOAKDM1ATRPV1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389580-B2 | Arylcyclopropylamines and methods of use | DUKE UNIVERSITY (US) | 2013-03-05 | — | — | US | disclosed |