Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 9/20 | 0.46 |
| ▸ | MAOA | P21397 | 6/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14747497 | 0.83 | TAS1R3 (0.46) | KDM1AMAOAMAOBEPHX2SMN1; SMN2 | |
| SCHEMBL14747476 | 0.81 | CYP1A2 (0.43) | KDM1AMAOAMAOBEPHX2RAB9A | |
| SCHEMBL2776196 | 0.80 | SMN1; SMN2 (0.55) | KDM1AMAOAMAOBEPHX2SMN1; SMN2 | |
| SCHEMBL2776191 | 0.80 | SMN1; SMN2 (0.55) | KDM1AMAOAMAOBEPHX2SMN1; SMN2 | |
| SCHEMBL7475866 | 0.76 | MMP3 (0.51) | EPHX2SMN1; SMN2 | |
| SCHEMBL10133116 | 0.73 | RAB9A (0.77) | EPHX2SMN1; SMN2NPC1RAB9ANPY5R | |
| SCHEMBL12972001 | 0.72 | KDM1A (0.71) | KDM1AMAOAMAOBEPHX2SMN1; SMN2 | |
| SCHEMBL15091992 | 0.72 | KDM1A (0.71) | KDM1AMAOAMAOBEPHX2SMN1; SMN2 | |
| SCHEMBL14747496 | 0.72 | SLC6A2 (0.43) | KDM1AMAOAMAOBEPHX2SMN1; SMN2 | |
| SCHEMBL22622348 | 0.72 | KDM1A (0.57) | KDM1AMAOBEPHX2SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389580-B2 | Arylcyclopropylamines and methods of use | DUKE UNIVERSITY (US) | 2013-03-05 | — | — | US | disclosed |