Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645883 | 0.83 | ALDH1A1 (0.62) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL14747747 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL11888426 | 0.79 | HCAR3 (0.48) | ALDH1A1POLBKMT2APKMTDP1 | |
| SCHEMBL11458496 | 0.78 | APEX1 (0.53) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL11887270 | 0.77 | CA1 (0.50) | ALDH1A1POLBKMT2AMAPTCA9 | |
| SCHEMBL913390 | 0.77 | ALDH1A1 (0.68) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL1564742 | 0.77 | KMT2A (0.67) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL30932792 | 0.77 | KMT2A (0.67) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL31647123 | 0.76 | ALDH1A1 (0.57) | ALDH1A1MEN1POLBKMT2APKM | |
| SCHEMBL10892487 | 0.75 | TSHR (0.58) | ALDH1A1MEN1POLBKMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389564-B2 | Proteasome inhibitors | TRIPHASE RESEARCH AND DEVELOPMENT I CORP. (CA) | 2013-03-05 | — | — | US | disclosed |