Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060072 | 0.84 | MEN1 (0.56) | ALDH1A1POLBMEN1KMT2APKM | |
| SCHEMBL1645883 | 0.84 | ALDH1A1 (0.62) | ALDH1A1POLBMEN1KMT2APKM | |
| SCHEMBL9349244 | 0.82 | ALDH1A1 (0.64) | ALDH1A1POLBMEN1KMT2APKM | |
| SCHEMBL11888407 | 0.81 | LMNA (0.52) | ALDH1A1POLBMEN1KMT2APKM | |
| SCHEMBL14747742 | 0.80 | ALDH1A1 (0.57) | ALDH1A1POLBMEN1KMT2APKM | |
| SCHEMBL11743952 | 0.79 | ALDH1A1 (0.50) | ALDH1A1POLBMEN1KMT2APKM | |
| SCHEMBL11449469 | 0.79 | MAPT (0.53) | ALDH1A1POLBMEN1KMT2APKM | |
| SCHEMBL4456811 | 0.78 | CA1 (0.50) | ALDH1A1POLBTSHRMAPTCYP3A4 | |
| SCHEMBL913390 | 0.78 | ALDH1A1 (0.68) | ALDH1A1POLBMEN1KMT2APKM | |
| SCHEMBL13969656 | 0.78 | PRMT5 (0.64) | ALDH1A1MEN1KMT2ATSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389564-B2 | Proteasome inhibitors | TRIPHASE RESEARCH AND DEVELOPMENT I CORP. (CA) | 2013-03-05 | — | — | US | disclosed |