Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | XPO1 | O14980 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27397739 | 0.83 | LMNA (0.55) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9141441 | 0.82 | MAPT (0.54) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL2529911 | 0.81 | CES2 (0.56) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8894645 | 0.79 | CES2 (0.46) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL5059081 | 0.79 | MAPT (0.55) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11815805 | 0.78 | TSHR (0.44) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL1202702 | 0.77 | CA12 (0.62) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11815157 | 0.77 | MAPT (0.46) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL11270791 | 0.76 | ALDH1A1 (0.57) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL25398382 | 0.76 | MAPT (0.41) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108864374-A | A kind of preparation method of the high water-retaining type polycarboxylate water-reducer of ethers | 科之杰新材料集团有限公司 | 2018-11-23 | — | — | CN | claimed |
| US-8389511-B2 | Bicyclic heterocyclic derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2013-03-05 | — | — | US | disclosed |