Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16152049 | 0.90 | DHODH (0.36) | DHODHSTAT3ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL8424459 | 0.86 | DHODH (0.39) | DHODHSTAT3ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7161177 | 0.80 | STAT3 (0.40) | DHODHSTAT3ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL27453797 | 0.80 | STAT3 (0.40) | DHODHSTAT3ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL1730532 | 0.79 | STAT3 (0.46) | DHODHSTAT3ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL70900 | 0.79 | STAT3 (0.46) | DHODHSTAT3ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL70901 | 0.79 | STAT3 (0.46) | DHODHSTAT3ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL2548351 | 0.78 | STAT3 (0.43) | DHODHSTAT3ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL9756774 | 0.78 | STAT3 (0.43) | DHODHSTAT3ALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL4621606 | 0.78 | STAT3 (0.43) | DHODHSTAT3ALDH1A1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1578771-B1 | Remodeling and glycoconjugation of peptides | NOVO NORDISK AS (DK) | 2013-03-06 | — | — | EP | disclosed |