Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2548348 | 1.00 | STAT3 (0.43) | STAT3ALDH1A1CA1CA2CA4 | |
| SCHEMBL4621606 | 1.00 | STAT3 (0.43) | STAT3ALDH1A1CA1CA2CA4 | |
| Acetone SCHEMBL9451549 | 0.95 | STAT3 (0.43) | STAT3ALDH1A1CA1CA2CA4 | |
| Acetone SCHEMBL8766802 | 0.95 | STAT3 (0.43) | STAT3ALDH1A1CA1CA2CA4 | |
| Acetone SCHEMBL8568091 | 0.95 | STAT3 (0.43) | STAT3ALDH1A1CA1CA2CA4 | |
| SCHEMBL19067491 | 0.94 | STAT3 (0.39) | STAT3ALDH1A1CA1CA2CA4 | |
| SCHEMBL4343843 | 0.94 | CYP2D6 (0.47) | STAT3ALDH1A1CA1CA2CA4 | |
| SCHEMBL4335282 | 0.94 | CYP2D6 (0.47) | STAT3ALDH1A1CA1CA2CA4 | |
| SCHEMBL140992 | 0.91 | STAT3 (0.46) | STAT3ALDH1A1CA1CA2CA4 | |
| SCHEMBL5471045 | 0.87 | STAT3 (0.43) | STAT3ALDH1A1CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736148-A | Production process of ketoconazole | 盐城凯利药业有限公司 | 2024-03-22 | — | — | CN | claimed |
| EP-0147847-B1 | OPTICALLY ACTIVE COMPOUNDS WITH ANTITUSSIVE AND CENTRAL SEDATIVE ACTIVITY, A PROCESS FOR THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING THE SAME | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-03-07 | — | — | EP | claimed |
| EP-0147847-A2 | Optically active compounds with antitussive and central sedative activity, a process for the preparation thereof and compositions containing the same | DOMPE' FARMACEUTICI S.p.A. (IT) | 1985-07-10 | — | — | EP | claimed |
| JP-5222019-A | — | — | None | — | — | JP | disclosed |
| US-12545666-B2 | Itraconazole analogs and use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2026-02-10 | — | — | US | disclosed |
| US-20250313572-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC (US) | 2025-10-09 | — | — | US | disclosed |
| US-20250092062-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC (US) | 2025-03-20 | — | — | US | disclosed |
| US-20240360111-A1 | ITRACONAZOLE ANALOGS AND USE THEREOF | THE JOHNS HOPKINS UNIVERSITY | 2024-10-31 | — | — | US | disclosed |
| US-12071430-B2 | Itraconazole analogs and use thereof | THE JOHNS HOPKINS UNIVERSITY (US) | 2024-08-27 | — | — | US | disclosed |
| US-20240228509-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | ABBVIE INC (US) | 2024-07-11 | — | — | US | disclosed |
| CN-117736148-A | Production process of ketoconazole | 盐城凯利药业有限公司 | 2024-03-22 | — | — | CN | disclosed |
| US-4408063-A | FROM A SULFONYLOXY HALOALCOHOL | MERCK & CO., INC. (US) | 1983-10-04 | — | — | US | disclosed |
| EP-0013856-B1 | NEW COMPOUNDS ASSOCIATING PEPTIDYL OR AMINOACYL RESIDUES TO LIPOPHILIC GROUPS AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID NEW COMPOUNDS | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1983-03-09 | — | — | EP | disclosed |
| EP-0006615-B1 | PROCESS FOR PREPARING EPIHALOHYDRIN ENANTIOMERS | MERCK & CO. INC. (US) | 1983-03-02 | — | — | EP | disclosed |
| US-4346042-A | Preparation of epihalohydrin enantiomers | MERCK & CO., INC. (US) | 1982-08-24 | — | — | US | disclosed |
| US-4335111-A | BACTERICIDES | AGENCE NATIONAL DE VALORISATION DE LA RECHERCHE (ANVAR) (FR) | 1982-06-15 | — | — | US | disclosed |
| US-4237250-A | Polyurethanes containing aryl sulfonic acid alkyl ester groups | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
| EP-0013856-A1 | New compounds associating peptidyl or aminoacyl residues to lipophilic groups and pharmaceutical compositions containing said new compounds | ANVAR Agence Nationale de Valorisation de la Recherche (FR) | 1980-08-06 | — | — | EP | disclosed |
| EP-0009075-A1 | Pyridyloxy-propanol amines and esters thereof, process for preparing the same and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1980-04-02 | — | — | EP | disclosed |
| EP-0006615-A1 | Process for preparing epihalohydrin enantiomers | MERCK & CO. INC. (US) | 1980-01-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360111-A1 | ITRACONAZOLE ANALOGS AND USE THEREOF | CYP3A4, SHH, GLI1 | STAT3 565/4885ALDH1A1 428/4885CA1 3810/4885 |
| US-20240228509-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | MCL1, BCL2A1, BCL2L10 | STAT3 1971/4885ALDH1A1 641/4885CA1 4115/4885 |
| US-20250092062-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | MCL1, BCL2A1, BCL2L10 | STAT3 1971/4885ALDH1A1 641/4885CA1 4115/4885 |
| US-20250313572-A1 | MACROCYCLIC MCL-1 INHIBITORS AND METHODS OF USE | MCL1, BCL2A1, BCL2L10 | STAT3 1971/4885ALDH1A1 641/4885CA1 4115/4885 |
| US-12545666-B2 | Itraconazole analogs and use thereof | SHH, SMO, GLI1 | STAT3 38/4885ALDH1A1 2379/4885CA1 2124/4885 |
| US-12071430-B2 | Itraconazole analogs and use thereof | CYP3A4, SHH, GLI1 | STAT3 565/4885ALDH1A1 428/4885CA1 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.