Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13104829 | 1.00 | STAT3 (0.43) | STAT3ALDH1A1MEN1KMT2ADHODH | |
| SCHEMBL9756838 | 1.00 | STAT3 (0.43) | STAT3ALDH1A1MEN1KMT2ADHODH | |
| SCHEMBL2176311 | 0.90 | GAA (0.45) | STAT3ALDH1A1MEN1KMT2ADHODH | |
| SCHEMBL4202226 | 0.85 | CA2 (0.41) | STAT3ALDH1A1MEN1KMT2ADHODH | |
| SCHEMBL6431507 | 0.85 | CA2 (0.41) | STAT3ALDH1A1MEN1KMT2ADHODH | |
| SCHEMBL4202231 | 0.85 | CA2 (0.41) | STAT3ALDH1A1MEN1KMT2ADHODH | |
| SCHEMBL13096089 | 0.84 | STAT3 (0.41) | STAT3ALDH1A1MEN1KMT2ADHODH | |
| SCHEMBL6069092 | 0.84 | STAT3 (0.41) | STAT3ALDH1A1MEN1KMT2ADHODH | |
| SCHEMBL4621606 | 0.83 | STAT3 (0.43) | STAT3ALDH1A1MEN1KMT2ADHODH | |
| SCHEMBL2548351 | 0.83 | STAT3 (0.43) | STAT3ALDH1A1MEN1KMT2ADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0316374-B1 | OPTICALLY ACTIVE COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 1991-07-31 | — | — | EP | disclosed |
| EP-0316374-A1 | OPTICALLY ACTIVE COMPOUNDS. | HOFFMANN LA ROCHE (CH) | 1989-05-24 | — | — | EP | disclosed |
| WO-1988008838-A1 | OPTICALLY ACTIVE COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1988-11-17 | — | — | WO | disclosed |