Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921912 | 0.90 | KDM4E (0.54) | HSD17B10LTA4HGAAKDM4EHPGD | |
| SCHEMBL17534098 | 0.90 | CHRNB4 (0.52) | MAPTHSD17B10LTA4HGAAKDM4E | |
| SCHEMBL10801528 | 0.87 | C5AR1 (0.52) | ALDH1A1KDM4EHPGDSLC6A2NPC1 | |
| SCHEMBL2442358 | 0.86 | MAOB (0.55) | MAPTLTA4HGAAALDH1A1KDM4E | |
| SCHEMBL19433111 | 0.86 | LTA4H (0.48) | MAPTHSD17B10LTA4HGAAALDH1A1 | |
| SCHEMBL30118840 | 0.86 | MAOB (0.55) | MAPTLTA4HGAAALDH1A1KDM4E | |
| SCHEMBL17549596 | 0.84 | LTA4H (0.47) | MAPTHSD17B10LTA4HGAAALDH1A1 | |
| SCHEMBL14747883 | 0.84 | ESR1 (0.49) | MAPTHSD17B10LTA4HGAAALDH1A1 | |
| SCHEMBL3026188 | 0.83 | CALM1 (0.51) | MAPTHSD17B10LTA4HGAAALDH1A1 | |
| SCHEMBL17534028 | 0.82 | LTA4H (0.46) | MAPTHSD17B10LTA4HGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143366-B2 | Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same | BIOCON LIMITED (IN) | 2012-03-27 | — | — | US | disclosed |