Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14748436 | 0.83 | PRKDC (0.43) | CRHBPCRHR2CYP2C19CYP1A2MEN1 | |
| SCHEMBL19622180 | 0.82 | HAO1 (0.33) | HAO1CYP2C19CYP1A2CYP2C9CYP3A4 | |
| SCHEMBL2232778 | 0.81 | KDM4E (0.41) | CRHBPCRHR2MERTKCYP2C19CYP1A2 | |
| SCHEMBL19622260 | 0.78 | CTSC (0.38) | CYP1A2MAPTL3MBTL1ALDH1A1GAA | |
| SCHEMBL24060727 | 0.77 | LMNA (0.40) | HAO1MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL19622259 | 0.74 | LMNA (0.41) | MAPTL3MBTL1PRKDCALDH1A1GAA | |
| SCHEMBL7863855 | 0.72 | HTT (0.44) | CYP2C19CYP1A2CYP2C9MEN1MAPT | |
| SCHEMBL29746806 | 0.72 | HTT (0.44) | CYP2C19CYP1A2CYP2C9MEN1MAPT | |
| SCHEMBL23243708 | 0.72 | MERTK (0.54) | CRHBPCRHR2MERTKMEN1MAPT | |
| SCHEMBL25590230 | 0.70 | PPARG (0.39) | HAO1MAPTL3MBTL1PRKDCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564857-A1 | Boron-containing small molecules as anti-inflammatory agents | Anacor Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |