SCHEMBL14748552

SCHEMBL14748552

CN1CCN(C(=O)C(C)(C)C)C(=O)C1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 6/20 0.36
KMT2A Q03164 1/20 0.36
LMNA P02545 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
THRB P10828 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
BLM P54132 1/20 0.32
MCOLN3 Q8TDD5 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
CYP1A2 P05177 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19427323 0.78 CYP1A2 (0.43) LMNACHRM2CHRM4CHRM5THRB
SCHEMBL12015352 0.75 ITGB1 (0.39) RIPK1KMT2ALMNATHRBBLM
SCHEMBL19421534 0.73 NPC1 (0.34) NPSR1CYP1A2TDP1
SCHEMBL14752964 0.73 CHRNB2 (0.40) KMT2ALMNABLMNPSR1HPGD
SCHEMBL12015351 0.72 LMNA (0.53) RIPK1KMT2ALMNATHRBBLM
SCHEMBL12015371 0.71 SMN1; SMN2 (0.51) RIPK1KMT2ALMNATHRBBLM
SCHEMBL17898504 0.71 TP53 (0.35) RIPK1KMT2ALMNACYP1A2
SCHEMBL17898502 0.69 KMT2A (0.32) RIPK1KMT2A
SCHEMBL12015370 0.69 SMN1; SMN2 (0.54) RIPK1KMT2ALMNATHRBBLM
SCHEMBL13621185 0.68 L3MBTL1 (0.35) KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SATORI PHARMACEUTICALS, INC. (US) 2013-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130060013-A1 Compounds useful for treating neurodegenerative disorders SNCA, HTT, CLN6 RIPK1 4241/4885KMT2A 2904/4885LMNA 1879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.